China Agricultural University Tracks Antibiotic Resistance Genes in Chinese Poultry Production

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Sampling surveys conducted by Chinese Agricultural University Shen Jianzhong and colleagues on Chinese farms, slaughterhouses, and supermarkets show that genes that allow bacteria to develop resistance to important antibiotics are commonly found in Chinese poultry production processes. The relevant results were published online in the early morning of February 7th in Nature - Microbiology.

Carbapenem and colistin are two types of "last line of defense" antibiotics that are used to treat potentially fatal human bacterial infections. Previously, people have identified two genes that are resistant to these antibiotics in the human food supply chain, but it is still unclear how these two genes were introduced into the agricultural field and spread.

This study shows that these antibiotic resistance genes are present in consumer meat products. The researchers found that the colistin used in the feed was associated with high levels of one of the genes in the hatchery, while the other gene was later introduced into the poultry, possibly through the external contamination of dogs, flies, and wild birds. The study brings new insights into how drug resistance genes enter and contaminate the human food chain, or can help shape new strategies to help reduce the emergence and further spread of these genes in the agricultural sector.

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