Invincible! A major breakthrough in cryopreservation life technology

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Preserving the human body through cryopreservation, hopefully reviving in the future - this has always been a technology that only exists in science fiction, but a new study has made people see hope in this regard.

The study claims that the memory formed by the experimental animals before freezing is still intact after thawing. Although the brain of the animal used for the experiment, the nematode, was much simpler than the human brain, the experiment still answered an important question about the freezing process.

In general, not many animals can be revived after cryopreservation, and they have never been successful in mammals. However, the question for scientists is, if humans can really resurrect from freezing, after the freezing process, can the individual's memory and personality remain the same?

If you don't use specific antifreeze chemicals, the freezing process will cause damage to the cells, but the specific impact will be unclear. Research by researchers from the refrigeration industry found that, at least for nematodes, the memory in the brain can remain intact during the freezing process.

Natasha Vita Moore, a researcher working for the Alco Life Extension Fund in Scottsdale, Arizona, said: "This is the first demonstration that memory can be preserved under cryoprotection." Further research on organisms with larger bodies and more complex nervous systems will be very beneficial for the study of cryoprotection, especially for memory retention after resuscitation."

About 300 people in the world are currently cryogenically frozen after their death. I hope that one day, the future technology will bring them back to life. But the industry is highly controversial and has been criticized by scientists. Although cryogenic freezing technology is a popular theme in sci-fi movies such as "The Undead," "Super Men," and "Ace," it has never succeeded in humans or any mammals. Executed.

Some species, such as frogs, polar fish and insects, survive after multiple freezes and thawing because they have a natural antifreeze in their cells that keeps the cells from freezing. For other animals, frozen ice crystals can rupture or damage cells. To stop this, the refrigeration industry has developed chemicals that protect cells. Techniques such as vitrification—fast freezing—can also help reduce the damage caused by freezing. This allows scientists to preserve mammalian cells, even a complete rabbit organ, and then resuscitate them, but has never succeeded in intact animals.

The use of these techniques in organs with such fine structures as the brain has always been debated. To answer this question, Dr. Vita Moore, Daniel Barranco of the University of Seville and the frozen biotechnology research team at the University of Seville, trained the C. elegans to smell them. A specific reaction is made when benzoin is used.

They conducted a series of experiments and published the results in the journal Rejuvenation Research. In the experiment, they used different cryoprotective methods for trained and untrained C. elegans.

They found that although only one-third of the nematodes that were frozen using the slow freezing method performed the same as the nematodes that were frozen using vitrification, both groups of nematodes retained specificity when smelling benzoin. The memory of the reaction.

The nematodes were kept in the frozen state for 30 minutes and then thawed. The results showed that these frozen nematodes performed similarly to the nematodes that were not frozen when they were tested for the memory of the response to their smell.

"Our results suggest that neither slow freezing nor vitrification will affect, alter or alter the mechanisms that regulate nematode olfactory imprinting and long-term memory," the researchers said. "Secondly, we believe that slow freezing And the cryoprotective process in vitrification does not affect, transform or alter this mechanism."

Many sci-fi movies involve cryopreservation techniques, such as "The End of the Day", but this technology has never been successful in humans or mammals.

The researchers tested C. elegans to make a specific response when they smelled an odor, and found that they still retain this memory after freezing.

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